Minis: Whence and Wherefore?
نویسنده
چکیده
In this issue of Neuron, Sara et al. find that spontaneously released miniature synaptic potentials arise from a pool of vesicles distinct from those released by neural activity. This modification of a basic tenet of the quantal hypothesis has important implications for the analysis of changes in synaptic transmission.
منابع مشابه
Are some minis multiquantal?
The amplitude distribution of miniature postsynaptic currents (minis) in many central neurons has a large variance and positive skew, but the sources of this variance and skew are unresolved. Recently it has been proposed that spontaneous Ca2+ influx into a presynaptic bouton with multiple release sites could cause spontaneous multiquantal minis by synchronizing release at all sites in the bout...
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عنوان ژورنال:
- Neuron
دوره 45 شماره
صفحات -
تاریخ انتشار 2005